Spondyloarthritis & psoriatic arthritis
Ultrasound-based detection of inflammatory changes for early diagnosis and risk model construction of psoriatic arthritis
Authors' conclusion
The implementation of the US models could streamline the diagnostic process for PsA in psoriasis patients, leading to expedited evaluations while maintaining diagnostic accuracy.
Study context
- Population
- Participants in the Department of Dermatology at West China Hospital (October 2018-April 2021) undergoing US examinations for early diagnosis of PsA in psoriasis
- Participants
- 1,256 participants
- Exposure
- Under 45 vs Over 45
- Under 45n = 767
- Over 45n = 489
- Outcome
- US model discrimination for PsA (derivation cohort)
Methodological detailsderivation and test cohort (7:3), LASSO and multivariable logistic regression, nomogram
- Derivation and test cohort (7:3)
- LASSO and multivariable logistic regression
- Nomogram
Main finding
As reported in the abstract
| Group | Ultrasonic variables in model | AUC |
|---|---|---|
| Under 45 | 11 | 0.83 (95% CI 0.78-0.87) |
| Over 45 | 16 | 0.83 (95% CI 0.78-0.88) |
Ultrasonic variables in model
Under 4511
Over 4516
AUC
Under 450.83 (95% CI 0.78-0.87)
Over 450.83 (95% CI 0.78-0.88)
Observational data: associations, not effects.
Original publication
Ultrasound-based detection of inflammatory changes for early diagnosis and risk model construction of psoriatic arthritis. Rheumatology (Oxford). Published 26 December 2023. doi:10.
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