Spondyloarthritis & psoriatic arthritis
Defining the Minimal Important Change and Meaningful Change Value of the Disease Activity Index for Psoriatic Arthritis: A Chinese Longitudinal Study
Authors' conclusion
A change in DAPSA of 8.4 is indicative of an MIC, offering physicians an additional means to contextualize the patient's perception of disease activity during treatment, and a change in DAPSA of 10.5 is likely to be regarded as MCV.
Study context
- Population
- Patients with psoriatic arthritis, Department of Dermatology, Xiangya Hospital, November 1, 2019, to April 1, 2023
- Participants
- 106 patients
- Outcome
- MIC and MCV of DAPSA (anchor: 5-point Likert scale of change in well-being since previous visit), and ES of DAPSA
Methodological detailsanchor-based method, linear regression analyses, single-centre
- Anchor-based method
- Linear regression analyses
- Single-centre
Main finding
As reported in the abstract
- Overall minimal important change (MIC)
- 8.4 (95% CI 0.01-16.75)
- MIC improvement
- 9.5 (95% CI 0.89-18.14)
- MIC deterioration
- 1.1 (95% CI −9.81 to 12.05)
- Overall meaningful change value (MCV)
- 10.5 (95% CI 4.34-16.72)
- MCV improvement
- 11.4 (95% CI 5.95-16.95)
- MCV deterioration
- 1.1 (95% CI −9.81 to 12.05)
- Effect size (ES)
- 0.6
Observational data: associations, not effects.
Original publication
Defining the Minimal Important Change and Meaningful Change Value of the Disease Activity Index for Psoriatic Arthritis: A Chinese Longitudinal Study. J Rheumatol. Published 15 March 2024. doi:10.
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