Spondyloarthritis & psoriatic arthritis

Enhanced surveillance for the detection of psoriatic arthritis in a UK primary care psoriasis population: results from the TUDOR trial

Rheumatology (Oxford)Published Randomised controlled trial

Authors' conclusion

in patients with psoriasis there was no evidence that early diagnosis of PsA by ES in primary care changes physical function at 24 months compared with SC.

Study context

Population
Patients with psoriasis in UK primary care, 135 general practitioner practices87 with PsA analysed (64 enhanced surveillance (ES), 23 standard care (SC))
Participants
2,225 patients
Comparison
Enhanced surveillance for PsA vs standard care in primary care psoriasis patients
  • ESn = 1,123
  • SCn = 1,102reference
Primary endpoint
HAQ Disability Index (HAQ-DI) in participants diagnosed with PsA
Follow-up
24 months post-registration
Methodological detailscluster, multicentre, prospective, parallel-group
  • Cluster
  • Multicentre
  • Prospective
  • Parallel-group

Primary result

As reported in the abstract

ES vs SCEstimate (95% CI)P value
HAQ-DI in participants diagnosed with PsA
aOR for HAQ-DI score of 0 0.64(0.17–2.38)
No evidence of a difference
aOR for higher (non-zero) HAQ-DI score 1.12(0.67–1.86)
P = 0.66

Original publication

Enhanced surveillance for the detection of psoriatic arthritis in a UK primary care psoriasis population: results from the TUDOR trial. Rheumatology (Oxford). Published 22 July 2024. doi:10.1093/rheumatology/keae374

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