Spondyloarthritis & psoriatic arthritis
Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort
Authors' conclusion
It shows that disease activity and physical function have a strong impact on ASAS HI, confirming it to be a valid construct of overall functioning and health in axSpA patients.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) in the Devenir des Spondylarthropathies Indifferénciées Récentes (DESIR) cohort, month 72analysed
- Participants
- 384 patients
- Outcome
- Interrelationships of disease outcomes (incl. ASDAS, BASFI) with the ASAS HI
- Follow-up
- Month 72
Methodological detailsprobabilistic Bayesian network modelling, month 72 data of the DESIR cohort
- Probabilistic Bayesian network modelling
- Month 72 data of the DESIR cohort
Main finding
As reported in the abstract
ASAS HI determinants (structural model)
Increase of ASAS HI per 1-unit increase of ASDAS
0.70 units
Increase of ASAS HI per 1-unit increase of Bath AS Functional Index (BASFI)
1.25 units
Observational data: associations, not effects.
Original publication
Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort. RMD Open. Published 20 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →