Spondyloarthritis & psoriatic arthritis
Trends to shorter diagnostic delay in spondyloarthritis patients during the last decades and association with clinical presentation: data from ASAS-COMOSPA study
Authors' conclusion
The proportion of patients with early SpA diagnosis improve from 15% before 1980 to 88% when first symptoms occurred after 2010. Type and number of initial clinical presentation were independent predictors of time to diagnosis.
Study context
- Population
- Patients with spondyloarthritis (SpA) diagnosis, international ASAS-COMOSPA study
- Participants
- 3,984 patients
- Exposure
- Decade of disease onset and initial clinical presentation vs diagnostic delay
- Outcome
- Time from disease onset to SpA diagnosis; early diagnosis (≤2 years)
Methodological detailsretrospective, international, multivariate logistic model
- Retrospective
- International
- Multivariate logistic model
Main finding
As reported in the abstract
Delay from disease onset to SpA diagnosis
P < 0.01
- Overall median delay from disease onset to SpA diagnosis (p25-75=0.3-9.8), years
- 2.9
Observational data: associations, not effects.
Further findings
Factors associated with early diagnosis (≤2 years), multivariate logistic model
- Age at disease onset, OR
- 1.02
- Axial symptom, OR
- 16.25
- Peripheral arthritis, OR
- 6.81
- Decade at disease onset, OR
- 3.80
- Extra-musculoskeletal manifestation, OR
- 2.89
- Female gender (inversely associated), OR
- 0.66
Original publication
Trends to shorter diagnostic delay in spondyloarthritis patients during the last decades and association with clinical presentation: data from ASAS-COMOSPA study. RMD Open. Published 31 January 2025. doi:10.
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