Spondyloarthritis & psoriatic arthritis
Global patterns and determinants of diagnostic delay in spondyloarthritis: insights from the ASAS-PerSpA international study
Authors' conclusion
DD was longer in axSpA and IBD-SpA compared with PsA, pSpA and other forms of SpA and associated with the phenotype of the presenting symptom.
Study context
- Population
- Patients with any SpA entity in the international ASAS-PerSpA study
- Participants
- 4,339 patients
- Exposure
- Diagnostic delay across SpA entities
- axSpAn = 2,622
- PsAn = 1,016
- pSpAn = 424
- IBD-SpAn = 110
- Other SpAn = 167
- Outcome
- Diagnostic delay (DD), by definition 1 (first symptom incl. extra-musculoskeletal manifestation) and definition 2 (first musculoskeletal manifestation as onset)
Methodological detailsancillary analysis of the ASAS-PerSpA study, international, multivariable linear regression
- Ancillary analysis of the ASAS-PerSpA study
- International
- Multivariable linear regression
Main finding
As reported in the abstract
Diagnostic delay, definition 2 (first musculoskeletal manifestation)
P < 0.001
Observational data: associations, not effects.
Further findings
Average DD, definition 2 vs definition 1 (all patients)
Factors associated with longer diagnostic delay (DD) (multivariable linear regression, axSpA, PsA, pSpA, IBD-SpA)
- Axial first manifestation, younger age at first symptom and older age at study inclusion associated with longer DD in the four SpA entities
Original publication
Global patterns and determinants of diagnostic delay in spondyloarthritis: insights from the ASAS-PerSpA international study. Rheumatology (Oxford). Published 26 September 2025. doi:10.
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