Spondyloarthritis & psoriatic arthritis
Association of validated patient reported outcome measures with patients’ self-reported disease status in axial spondyloarthritis
Authors' conclusion
Patients' self-reported disease status was well captured by ASDAS and BASDAI in most clinical visits. Other investigated measures used in clinical trials failed to capture patients' self-reported disease status in a large proportion of visits.
Study context
- Population
- axSpA patients, initial and last five routine clinical visits
- Participants
- 557 patients3,120 visits
- Exposure
- Validated PROs vs patients' self-reported disease status
- Outcome
- Association of validated PROs with patients' self-reported disease status (very good, mild, severe, very severe)
Methodological detailsmixed models
- Mixed models
Main finding
As reported in the abstract
Self-reported disease status by validated measure category (% of visits)
- Very good or mild status, inactive ASDAS
- 98.7%
- Very good or mild status, low ASDAS
- 90.9%
- Very good or mild status, high ASDAS
- 67.9%
- Very good or mild status, very high ASDAS
- 39.3%
- Severe or very severe status, ASAS20 achieved
- 15.1%
- Severe or very severe status, ASAS40 achieved
- 7.2%
- Severe or very severe status, ASAS partial remission achieved
- 0.6%
- Severe or very severe status, ASAS20 not achieved
- 26.0%
- Severe or very severe status, ASAS40 not achieved
- 25.1%
- Severe or very severe status, ASAS partial remission not achieved
- 30.1%
Observational data: associations, not effects.
Original publication
Association of validated patient reported outcome measures with patients’ self-reported disease status in axial spondyloarthritis. Rheumatology (Oxford). Published 5 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →