Spondyloarthritis & psoriatic arthritis

Instrument selection for the assessment of peripheral arthritis in axial and peripheral spondyloarthritis: an ASAS project

Ann Rheum DisPublished Systematic review with individual patient data analysis and consensus

Authors' conclusion

DAPSA44 demonstrated the most adequate measurement performance across axSpA and pSpA and was endorsed by ASAS as the recommended instrument for assessing disease activity related to peripheral arthritis in pSpA clinical research.

Study context

Population
Axial spondyloarthritis (axSpA) and peripheral spondyloarthritis (pSpA) with peripheral arthritis, clinical research13 randomised controlled trials (RCTs)
Comparison
Candidate instruments for peripheral arthritis disease activity: composite instruments (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Axial Spondyloarthritis Disease Activity Score (ASDAS), DAPSA44) vs single-item measures and joint counts
Outcome
Most appropriate instrument to assess disease activity related to peripheral arthritis in axSpA and pSpA
Methodological detailsOMERACT framework, two systematic literature review (SLRs), individual patient data from RCTs, working group discussion, ASAS consensus voting
  • OMERACT framework
  • Two SLRs
  • Individual patient data from RCTs
  • Working group discussion
  • ASAS consensus voting

Recommendations

As reported in the abstract

Instrument selection

ASAS voting agreement for DAPSA44 as preferred instrument, axSpA

92%

ASAS voting agreement for DAPSA44 as preferred instrument, pSpA

97%

Original publication

Instrument selection for the assessment of peripheral arthritis in axial and peripheral spondyloarthritis: an ASAS project. Ann Rheum Dis. Published 7 July 2026. doi:10.1016/j.ard.2026.06.002

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