Spondyloarthritis & psoriatic arthritis
Measurement properties of instruments assessing peripheral arthritis disease activity in spondyloarthritis: a systematic literature review
Authors' conclusion
Evidence supporting instruments to assess peripheral arthritis in spondyloarthritis remains scarce, especially in axSpA. Composite instruments in pSpA performed better, but evidence gaps persist
Study context
- Population
- Adults with axSpA or peripheral spondyloarthritis (pSpA) and peripheral arthritis; instruments: Patient Global Assessment (PGA), swollen joint count (66/44), tender joint count (68/44), C reactive protein (CRP), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Axial Spondyloarthritis Disease Activity Score (ASDAS), DAPSA and Disease Activity Score using 44 joints8 studies
- Comparison
- axSpA vs pSpA
- Outcome
- Measurement properties: construct validity (correlation hypotheses; known-groups discrimination) and discrimination (test-retest reliability, responsiveness; clinical trial discrimination; thresholds of meaning)
Methodological detailsOMERACT Good Methods Checklist risk of bias, evidence synthesised following OMERACT rules (GREEN-good; AMBER-adequate; RED-poor performance), Medline/EMBASE/Cochrane searched until February 2025
- OMERACT Good Methods Checklist risk of bias
- Evidence synthesised following OMERACT rules (GREEN-good; AMBER-adequate; RED-poor performance)
- Medline/EMBASE/Cochrane searched until February 2025
Main finding
As reported in the abstract
Measurement properties of peripheral arthritis disease activity instruments
- axSpA: evidence limited to PGA, CRP and BASDAI, rating mostly AMBER for construct validity, longitudinal construct validity and discrimination in clinical trials
- pSpA: composite instruments showed better results, with BASDAI, ASDAS and DAPSA rating mostly GREEN
- No study provided test-retest reliability or thresholds of meaning
Original publication
Measurement properties of instruments assessing peripheral arthritis disease activity in spondyloarthritis: a systematic literature review. RMD Open. Published 29 June 2026. doi:10.
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