Spondyloarthritis & psoriatic arthritis
Comparative analysis of instruments measuring peripheral arthritis activity in Spondyloarthritis: a measurement properties study in 13 randomised controlled trial (RCTs)
Authors' conclusion
Composite scores, such as BASDAI, ASDAS and DAPSA44, generally demonstrated more robust performance than single-item instruments, expanding the evidence base for the final instrument-selection phase.
Study context
- Population
- Patients in RCTs in axSpA (restricted to those with peripheral arthritis at baseline) or pSpA13 RCTs (10 axSpA, 3 pSpA)
- Comparison
- Instruments measuring peripheral arthritis activity
- Outcome
- Measurement properties of instruments for peripheral arthritis
Methodological details13 RCTs, OMERACT-based GREEN/AMBER/RED ratings, risk of bias evaluated
- 13 RCTs
- OMERACT-based GREEN/AMBER/RED ratings
- Risk of bias evaluated
Pooled result
As reported in the abstract
- axSpA: construct validity and thresholds of meaning AMBER/GREEN for all instruments
- axSpA: test-retest reliability RED only for Patient Global Assessment (PGA)
- axSpA: responsiveness consistently GREEN
- axSpA: trial discrimination RED for single-item instruments, consistently GREEN for composite scores
- pSpA: most instruments AMBER/GREEN; SJC44 RED discrimination
Further pooled results
Baseline peripheral arthritis
- axSpA trials: patients with peripheral arthritis
- 25-51%
- axSpA: median SJC44 across studies
- 2-3
- pSpA: median SJC44 range
- 2-5
Original publication
Comparative analysis of instruments measuring peripheral arthritis activity in Spondyloarthritis: a measurement properties study in 13 RCTs. RMD Open. Published 25 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →