Lupus & antiphospholipid syndrome
The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases
Authors' conclusion
This data-driven and expert/patient consensus-based process has proposed 39 candidate items, some with subitems, and definitions for a revised SDI.
Study context
- Population
- International SLE experts and patients (Delphi panel); development of a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI)Delphi panel, 35 countries
- Participants
- 146 experts
- Outcome
- Item generation and reduction for a revised SDI
Methodological detailsDelphi exercise, literature review, item reduction committee, Delphi rounds excluded items with median appropriateness score ≤4 of 9; 14-member item reduction committee removed items not reflecting damage, rare or not feasible
- Delphi exercise
- Literature review
- Item reduction committee
- Delphi rounds excluded items with median appropriateness score ≤4 of 9; 14-member item reduction committee removed items not reflecting damage, rare or not feasible
Recommendations
As reported in the abstract
- Items nominated by Delphi exercise
- 2,256
- Items identified by literature review
- 117
- Candidate items after removing redundancies
- 226
- Final items
- 39 items across 13 domains
- Original SDI items removed (incl. proteinuria and cranial neuropathy)
- 11
- Items with proposed severity-based subitems
- 17 items (43.6%)
Original publication
The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases. Arthritis Care Res (Hoboken). Published 12 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →