Lupus & antiphospholipid syndrome
Association of the Systemic Lupus International Collaborating Clinics Frailty Index and Damage Accrual in Longstanding Systemic Lupus Erythematosus
Primary result · Damage accrual per 0.05-unit increase in baseline SLICC-FIResult — go to the resultOdds ratio 1.28 95% CI 1.01–1.63Authors' conclusion
In a prevalent cohort of women with established SLE, higher baseline SLICC-FI scores were associated with a higher risk of subsequent damage accrual at 5-year follow-up.
Study context
- Population
- Adult women with systemic lupus erythematosus (SLE) (1997 revised American College of Rheumatology (ACR) criteria) from the Chicago Lupus Database; longstanding SLE149 in 5-year analysis
- Participants
- 185 women
- Comparison
- Baseline Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) score and damage accrual at 5-year follow-up
- Primary endpoint
- Damage accrual (SDI) per 0.05 increase in baseline SLICC-FI
- Follow-up
- 5-year follow-up
Methodological detailsprospective cohort, external validation, unadjusted and adjusted logistic regression
- Prospective cohort
- External validation
- Unadjusted and adjusted logistic regression
Primary result
As reported in the abstract
Damage accrual per 0.05-unit increase in baseline SLICC-FI
Odds ratio
1.28
95% CI 1.01–1.63
Per 0.05-unit increase in baseline SLICC-FI
OR 1.28 (95% CI 1.01–1.63)
Per 0.05-unit increase in baseline SLICC-FI, as printed
Further findings
Baseline SLICC-FI and frailty
- Mean ± SD SLICC-FI score
- 0.18 ± 0.08
- Frail (SLICC-FI score >0.21)
- 36%
Original publication
Association of the Systemic Lupus International Collaborating Clinics Frailty Index and Damage Accrual in Longstanding Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). Published 31 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →