Lupus & antiphospholipid syndrome
Systemic Lupus International Collaborating Clinics-Frailty Index predicts hospitalisations in the Almenara Lupus Cohort
Authors' conclusion
The SLICC-FI predicted hospitalisations in patients with SLE, independent of other well-known risk factors.
Study context
- Population
- Patients with SLE from a single-centre Latin American prevalent cohort (Almenara Lupus Cohort)273 (92.5%) female
- Participants
- 295 patients
- Exposure
- Baseline Systemic Lupus International Collaborating Clinics-Frailty Index (SLICC-FI) as predictor of hospitalisations
- Outcome
- Hospitalisations (number and duration in days) during follow-up
- Follow-up
- First 3 years from baseline visit
Methodological detailssingle-centre, prevalent cohort, negative binomial regression
- Single-centre
- Prevalent cohort
- Negative binomial regression
Main finding
As reported in the abstract
Hospitalisations per 0.05 increase in baseline SLICC-FI · 3 years
Number of hospitalisations, IRR
1.671
95% CI 1.385 to 2.016
Days of hospitalisation, IRR
2.018
95% CI 1.715 to 2.375
Observational data: associations, not effects.
Further findings
Baseline SLICC-FI and frailty
- Mean SLICC-FI (SD 0.05)
- 0.18
- Frail patients, n (29.2%)
- 86
Hospitalisation burden per patient-year · 3 years
- Mean hospitalisations per patient-year (SD 0.8)
- 0.4
- Mean days hospitalised per patient-year (SD 7.6)
- 3.1
Modified SLICC-FI (damage-related deficits excluded)
- Also predicted hospitalisations in both number and days
Original publication
Systemic Lupus International Collaborating Clinics-Frailty Index predicts hospitalisations in the Almenara Lupus Cohort. Lupus Sci Med. Published 13 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →