The feasibility of existing juvenile arthritis disease activity score (JADAS10) cut-off values in clinical practice: a study of data from The Finnish Rheumatology Quality Register
Authors' conclusion
We found the cut-offs proposed by Consolaro et al. to be the most feasible, since these cut-off levels for CID do not result in the misclassification of active disease as remission, and the proportion of patients with AJC > 1 in the LDA group is lowest using these cut-offs.
Study context
- Population
- Patients with non-systemic JIA in The Finnish Rheumatology Quality Register (FinRheuma)
- Exposure
- Trincianti vs Backström vs Consolaro JADAS10/clinical JADAS10 (cJADAS10) cut-offs
- Outcome
- Proportion of patients with AJC above zero when classified as CID or LDA by existing JADAS10/cJADAS10 cut-offs
Methodological detailsregister data (FinRheuma)
- Register data (FinRheuma)
Main finding
As reported in the abstract
CID: proportion with AJC > 0
- Significantly larger proportion with active joint count (AJC) > 0 in clinically inactive disease (CID) using Trincianti cut-offs than other cut-offs
Observational data: associations, not effects.
Further findings
| Outcome | Trincianti | Backström | Consolaro |
|---|---|---|---|
| LDA, polyarticular patients: proportion with AJC of two (JADAS10/cJADAS10) | 35%/29% | 11%/10% | 7%/3% |
Low disease activity (LDA), polyarticular patients: proportion with AJC of two (JADAS10/cJADAS10)
- Significantly larger proportion with Trincianti vs Backström and Consolaro cut-offs
Original publication
The feasibility of existing JADAS10 cut-off values in clinical practice: a study of data from The Finnish Rheumatology Quality Register. Pediatr Rheumatol Online J. Published 14 April 2023. doi:10.
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