When to address fatigue in juvenile idiopathic arthritis during clinical visits based on the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)
Authors' conclusion
The proxy can be used to estimate whether issues with fatigue should be explored during clinical visits.
Study context
- Population
- Patients with Juvenile Idiopathic Arthritis (JIA) at the Wilhelmina Children's Hospital (WCH); proxy re-used in the EPOCA cohort
- Participants
- 105 WCH patients
- Comparison
- JAMAR Quality of Life (QoL) proxy vs CIS-8 severe fatigue cut-off
- Outcome
- Predictive value and cut-off of the JAMAR QoL proxy for severe fatigue (CIS-8)
Methodological detailsbinary logistic regression, ROC analysis, external comparison cohort (EPOCA)
- Binary logistic regression
- ROC analysis
- External comparison cohort (EPOCA)
Performance
As reported in the abstract
Prediction of severe fatigue (CIS-8) by the proxy, cut-off score ≥1
- Proxy significant predictor of severe fatigue controlled for age, sex and disease activity
- P < 0.001
Further findings
Correlation of QoL items with severe fatigue
- Item 3 correlation
- 0.644
- Item 9 correlation
- 0.565
- Strongest correlations with severe fatigue
Patients in whom fatigue should be addressed per proxy
- WCH patients
- 58.1%
- EPOCA cohort
- 56.6%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
When to address fatigue in juvenile idiopathic arthritis during clinical visits based on the JAMAR. Rheumatology (Oxford). Published 9 June 2025. doi:10.
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