Systemic sclerosis & Raynaud's
Surgical management of digital ulcers in systemic sclerosis: A systematic literature review
Authors' conclusion
Several surgical approaches for SSc-DUs have demonstrated some degree of safety and effectiveness for DU healing.
Study context
- Population
- Adult patients with systemic sclerosis (SSc) and digital ulcers treated with local surgery13 articles
- Comparison
- Local surgical treatments for SSc digital ulcers
- Outcome
- Safety and efficacy (DU healing rate) of local surgical management
Methodological detailsPICO framework, risk of bias assessment with validated tools, dual independent screening, 7 databases searched until August 2022; 13 of 899 articles included
- PICO framework
- Risk of bias assessment with validated tools
- Dual independent screening
- 7 databases searched until August 2022; 13 of 899 articles included
Main finding
As reported in the abstract
DU healing rate
Autologous fat grafting
66-100 %
Adipose-derived stromal vascular fraction grafting
32-60 %
Bone marrow derived cell transplantation
100 %
Surgical sympathectomy
81 %
median
Microsurgical revascularisation/arteriolysis
100 %
Safety
| Outcome | Values |
|---|---|
| Complications of microsurgical revascularisation/arteriolysis | Microsurgical revascularisation/arteriolysis 0 events |
Original publication
Surgical management of digital ulcers in systemic sclerosis: A systematic literature review. Semin Arthritis Rheum. Published 26 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →