Systemic sclerosis & Raynaud's
Regenerative treatments for scleroderma in cutaneous manifestations of the face: a systematic review
Authors' conclusion
Autologous regenerative treatments hold potential for alleviating cutaneous manifestations of the face in scleroderma.
Study context
- Population
- Scleroderma patients with cutaneous manifestations of the face18 studies
- Comparison
- Autologous regenerative treatments (autologous fat grafting, platelet-rich plasma, stromal vascular fraction, adipose-derived stem cells) for facial cutaneous manifestations of scleroderma
- Outcome
- Effectiveness of autologous regenerative treatments
Methodological detailsSearch of PubMed, Embase, Web of Science Core Collection, Cochrane CENTRAL and CINAHL, Methodological quality assessed with the Effective Public Health Practice Project tool
- Search of PubMed, Embase, Web of Science Core Collection, Cochrane CENTRAL and CINAHL
- Methodological quality assessed with the Effective Public Health Practice Project tool
Pooled result
As reported in the abstract
- Most studies showed improvements of symptoms, but no treatment was considered superior
- Methodological quality weak (n=15) and moderate (n=3)
Original publication
Regenerative treatments for scleroderma in cutaneous manifestations of the face: a systematic review. Clin Exp Rheumatol. Published 11 March 2024. doi:10.
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