Vasculitis & polymyalgia rheumatica
Stable incidence but increase in prevalence of ANCA-associated vasculitis in southern Sweden: a 23-year study
Authors' conclusion
The incidence of AAV in southern Sweden was found stable over the course of 23 years; while the prevalence has increased
Study context
- Population
- Adults (≥18 years) diagnosed with antibody-associated vasculitis (AAV) in 1997–2019 in 14 municipalities of southern Sweden (adult population 623,872 in 2019)median age 67.5 years, 47% female
- Participants
- 374 adults
- Exposure
- Granulomatosis with polyangiitis (GPA) vs microscopic polyangiitis (MPA) vs eosinophilic GPA (EGPA)
- GPAn = 192
- MPAn = 159
- EGPAn = 23
- Outcome
- Average annual incidence and point prevalence of AAV per million adults
- Follow-up
- 1997-2019; prevalence on 01 January 2020
Methodological detailsdefined geographical area, case record review, European Medicines Agency algorithm classification
- Defined geographical area
- Case record review
- European Medicines Agency algorithm classification
Main finding
As reported in the abstract
Average annual incidence/million adults · 1997-2019
- AAV overall incidence/million adults
- 30.1 (95% CI 27.0 to 33.1)
Observational data: associations, not effects.
Further findings
AAV incidence by period
- 1997-2003 (/million)
- 30.3
- 2004-2011 (/million)
- 30.4
- 2012-2019 (/million)
- 29.5
- Incidence was stable during the study period
AAV incidence by age
- Incidence increased with age; highest in age group 70-84 years (/million adults)
- 96
AAV point prevalence/million adults · 1 January 2020
- Overall
- 428
- Males
- 480
- Females
- 378
Original publication
Stable incidence but increase in prevalence of ANCA-associated vasculitis in southern Sweden: a 23-year study. RMD Open. Published 9 March 2023. doi:10.
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