Vasculitis & polymyalgia rheumatica

Investigating the concomitance of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides and inflammatory bowel disease (IBD)

Semin Arthritis RheumPublished Retrospective study

Authors' conclusion

Objective observation and deductions from this study raise the concern for a possible pathogenic association of ANCA associated vasculitis and inflammatory bowel disease

Study context

Population
Patients with AAV (granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) or eosinophilic granulomatosis with polyangiitis (EGPA)) and overlapping IBD (Crohn's disease or ulcerative colitis), 01/01/2020 to 08/03/2023
Participants
39 patients
Exposure
GPA vs MPA vs EGPA
  • GPAn = 20
  • MPAn = 6
  • EGPAn = 4
Outcome
Order of diagnoses: IBD vs ANCA vasculitis

Main finding

As reported in the abstract

IBD diagnosis preceded the diagnosis of ANCA vasculitis

77.8 %

Observational data: associations, not effects.

Further findings

Events

OutcomeGPAMPAEGPA
Ulcerative colitis1342
Crohn's disease622
Unspecified IBD1— not stated in the abstract— not stated in the abstract

— not stated in the abstract

Original publication

Investigating the concomitance of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides and inflammatory bowel disease (IBD). Semin Arthritis Rheum. Published 23 April 2024. doi:10.1016/j.semarthrit.2024.152452

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