Vasculitis & polymyalgia rheumatica
Investigating the concomitance of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides and inflammatory bowel disease (IBD)
Authors' conclusion
Objective observation and deductions from this study raise the concern for a possible pathogenic association of ANCA associated vasculitis and inflammatory bowel disease
Study context
- Population
- Patients with AAV (granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) or eosinophilic granulomatosis with polyangiitis (EGPA)) and overlapping IBD (Crohn's disease or ulcerative colitis), 01/01/2020 to 08/03/2023
- Participants
- 39 patients
- Exposure
- GPA vs MPA vs EGPA
- GPAn = 20
- MPAn = 6
- EGPAn = 4
- Outcome
- Order of diagnoses: IBD vs ANCA vasculitis
Main finding
As reported in the abstract
IBD diagnosis preceded the diagnosis of ANCA vasculitis
77.8 %
Observational data: associations, not effects.
Further findings
Events
| Outcome | GPA | MPA | EGPA |
|---|---|---|---|
| Ulcerative colitis | 13 | 4 | 2 |
| Crohn's disease | 6 | 2 | 2 |
| Unspecified IBD | 1 | — not stated in the abstract | — not stated in the abstract |
— not stated in the abstract
Original publication
Investigating the concomitance of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides and inflammatory bowel disease (IBD). Semin Arthritis Rheum. Published 23 April 2024. doi:10. 1016/ j. semarthrit. 2024. 152452
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