Spondyloarthritis & psoriatic arthritis

Smoking and alcohol consumption are associated with peripheral musculoskeletal involvement in patients with spondyloarthritis (including psoriatic arthritis). Results from the ASAS-PerSpA study

Semin Arthritis RheumPublished Cross-sectional study

Authors' conclusion

Taking into account the country, smoking and alcohol are associated with a lower prevalence of peripheral manifestations.

Study context

Population
Patients from the worldwide ASAS-PerSpA study with axial SpA (axSpA), peripheral SpA (pSpA) or psoriatic arthritis (PsA)
Participants
4,181 patients
Exposure
Smoking status and alcohol consumption vs absence, for peripheral musculoskeletal manifestations
Outcome
Presence of peripheral musculoskeletal manifestations (arthritis, enthesitis or dactylitis) and their location
Methodological detailsworldwide, generalised linear mixed models with country as random effect
  • Worldwide
  • Generalised linear mixed models with country as random effect

Main finding

As reported in the abstract

  • axSpA: smoking associated with lower prevalence of any peripheral manifestation; current alcohol associated with lower prevalence of both current arthritis and current enthesitis
  • pSpA: current alcohol associated with lower prevalence of current arthritis or enthesitis
  • PsA: significant association for arthritis with smoking and for enthesitis with alcohol; current alcohol associated with lower prevalence of current arthritis or enthesitis

Observational data: associations, not effects.

Original publication

Smoking and alcohol consumption are associated with peripheral musculoskeletal involvement in patients with spondyloarthritis (including psoriatic arthritis). Results from the ASAS-PerSpA study. Semin Arthritis Rheum. Published 30 November 2022. doi:10.1016/j.semarthrit.2022.152146

Composed by AI from the published abstract and checked against it. How Briefs are made →

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