Spondyloarthritis & psoriatic arthritis
Smoking and alcohol consumption are associated with peripheral musculoskeletal involvement in patients with spondyloarthritis (including psoriatic arthritis). Results from the ASAS-PerSpA study
Authors' conclusion
Taking into account the country, smoking and alcohol are associated with a lower prevalence of peripheral manifestations.
Study context
- Population
- Patients from the worldwide ASAS-PerSpA study with axial SpA (axSpA), peripheral SpA (pSpA) or psoriatic arthritis (PsA)
- Participants
- 4,181 patients
- Exposure
- Smoking status and alcohol consumption vs absence, for peripheral musculoskeletal manifestations
- Outcome
- Presence of peripheral musculoskeletal manifestations (arthritis, enthesitis or dactylitis) and their location
Methodological detailsworldwide, generalised linear mixed models with country as random effect
- Worldwide
- Generalised linear mixed models with country as random effect
Main finding
As reported in the abstract
- axSpA: smoking associated with lower prevalence of any peripheral manifestation; current alcohol associated with lower prevalence of both current arthritis and current enthesitis
- pSpA: current alcohol associated with lower prevalence of current arthritis or enthesitis
- PsA: significant association for arthritis with smoking and for enthesitis with alcohol; current alcohol associated with lower prevalence of current arthritis or enthesitis
Observational data: associations, not effects.
Original publication
Smoking and alcohol consumption are associated with peripheral musculoskeletal involvement in patients with spondyloarthritis (including psoriatic arthritis). Results from the ASAS-PerSpA study. Semin Arthritis Rheum. Published 30 November 2022. doi:10. 1016/ j. semarthrit. 2022. 152146
Composed by AI from the published abstract and checked against it. How Briefs are made →