Risk perception, well-being, depression and anxiety in children and adolescents with rheumatic diseases during the COVID-19 pandemic - results from the prospective multicenter KICK-COVID study in Germany
Authors' conclusion
The perception of health risk due to SARS-CoV2 infection was not paralleled by an impairment of mental health, which were, however, significantly correlated with self-rated health status and functional capacity, highlighting the importance of patient-reported outcome assessment.
Study context
- Population
- Children and adolescents with juvenile rheumatic diseases during the COVID-19 pandemic, Germany, routine visits June to December 202169% female, 50% adolescents
- Participants
- 1,356 children
- Exposure
- Adolescents vs parents of children < 12 years
- Outcome
- Perceived health risk due to SARS-CoV2 (NRS 0-10) and perceived stress
Methodological detailsmulticentre, observational, linked to the National Pediatric Rheumatology Database, multivariable regression, Data collected at routine visits from June to December 2021
- Multicentre
- Observational
- Linked to the National Pediatric Rheumatology Database
- Multivariable regression
- Data collected at routine visits from June to December 2021
Main finding
As reported in the abstract
Median perceptions of health risk (PHR) (numeric rating scale (NRS) 0-10), IQR 2-6
4
Median perceived stress, IQR 1-6
3
Observational data: associations, not effects.
Further findings
Median
| Outcome | Adolescents | Children < 12 years |
|---|---|---|
| Well-being (WHO-5 score) | 60 (IQR 40–76) | 80 (IQR 68–84) |
Well-being (WHO-5 score)
- Significantly lower WHO-5 in adolescents (worse well-being)
Moderate to severe symptoms of depression (PHQ-9) and anxiety (GAD-7) in adolescents
- Moderate to severe depression symptoms, adolescents
- 14.3%
- Moderate to severe anxiety symptoms, adolescents
- 12.3%
Factors associated with PHR and mental health
- PHR significantly higher in SLE, MTX or bDMARD therapy
- Lower WHO-5 or higher PHQ-9 or GAD-7 only associated with poorer patient-reported health status and physical functioning
Original publication
Risk perception, well-being, depression and anxiety in children and adolescents with rheumatic diseases during the COVID-19 pandemic - results from the prospective multicenter KICK-COVID study in Germany. Pediatr Rheumatol Online J. Published 18 April 2024. doi:10.
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