Kawasaki disease in Kenya and review of the African literature
Authors' conclusion
This is the first publication on Kawasaki disease from Kenya and one of the largest reports from sub-Saharan Africa. It is the first to have a complete review of the number of published cases from the African continent.
Study context
- Population
- In-patients with a discharge diagnosis of Kawasaki disease over 2 different 5-year periods at two pediatric hospitals in Nairobi, Kenya12 (52.2%) incomplete disease
- Participants
- 23 participants
- Outcome
- Clinical findings, diagnostic workup and treatment of Kawasaki disease in Kenya
Methodological detailstwo paediatric hospitals, medical record review
- Two paediatric hospitals
- Medical record review
Main finding
As reported in the abstract
- Incomplete disease
- 12 (52.2%)
- Mean age, years (SD+/−2.2; range 0.3-10.3)
- 2.3
- Male to female ratio
- 1:1
- Mean duration of fever at diagnosis, days (SD+/−4.7; range 2-20)
- 8.3
- Thrombocytosis at diagnosis
- 52% (12/23)
- Treated with IV immunoglobulin
- 21 (91.3%)
- Baseline echocardiograms performed
- 95.7% (22/23)
- Abnormal baseline echocardiograms
- 3 (13.6%)
Observational data: associations, not effects.
Further findings
Literature review of Kawasaki disease in children across Africa
- Publications with documented cases
- 79
- Countries across the African continent
- 22
- Total patients, including this report
- 1115
- Reported cases from sub-Saharan Africa
- 153 (13.7%)
Original publication
Kawasaki disease in Kenya and review of the African literature. Pediatr Rheumatol Online J. Published 14 April 2024. doi:10. 1186/ s12969-024-00977-1
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