Pediatric rheumatology

Kawasaki disease in Kenya and review of the African literature

Pediatr Rheumatol Online JPublished Retrospective cross-sectional study with literature review

Authors' conclusion

This is the first publication on Kawasaki disease from Kenya and one of the largest reports from sub-Saharan Africa. It is the first to have a complete review of the number of published cases from the African continent.

Study context

Population
In-patients with a discharge diagnosis of Kawasaki disease over 2 different 5-year periods at two pediatric hospitals in Nairobi, Kenya12 (52.2%) incomplete disease
Participants
23 participants
Outcome
Clinical findings, diagnostic workup and treatment of Kawasaki disease in Kenya
Methodological detailstwo paediatric hospitals, medical record review
  • Two paediatric hospitals
  • Medical record review

Main finding

As reported in the abstract

Incomplete disease
12 (52.2%)
Mean age, years (SD+/−2.2; range 0.3-10.3)
2.3
Male to female ratio
1:1
Mean duration of fever at diagnosis, days (SD+/−4.7; range 2-20)
8.3
Thrombocytosis at diagnosis
52% (12/23)
Treated with IV immunoglobulin
21 (91.3%)
Baseline echocardiograms performed
95.7% (22/23)
Abnormal baseline echocardiograms
3 (13.6%)

Observational data: associations, not effects.

Further findings

Literature review of Kawasaki disease in children across Africa

Publications with documented cases
79
Countries across the African continent
22
Total patients, including this report
1115
Reported cases from sub-Saharan Africa
153 (13.7%)

Original publication

Kawasaki disease in Kenya and review of the African literature. Pediatr Rheumatol Online J. Published 14 April 2024. doi:10.1186/s12969-024-00977-1

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