Systematic Review of Health‐Related Quality of Life Impact in Juvenile Localized Scleroderma
Authors' conclusion
Overall, quantitative studies did not report a statistically significant impairment in HRQoL in JLS. However, qualitative studies (focus groups) reported significant psychosocial impacts related to JLS.
Study context
- Population
- Pediatric patients with juvenile localized scleroderma (morphea); literature published 2000–2020, English language
- Participants
- 690 patients13 studies
- Outcome
- Measures of HRQoL, psychosocial functioning, self-perception and treatment burden
Methodological detailsthematic synthesis, descriptive analysis
- Thematic synthesis
- Descriptive analysis
Pooled result
As reported in the abstract
- Children's Dermatology Life Quality Index (6 studies): little to no effect on health-related quality of life (HRQoL)
- Health-Related Quality of Life in Children and Adolescents Questionnaire (1 study): no differences between children with juvenile localized scleroderma (JLS) or atopic dermatitis and healthy controls
- Self-perception questionnaire (1 study): normal self-worth in JLS
- Focus groups (2 studies): elevated stress, decreased self-worth, "feeling different" and bullying/teasing in JLS, associated with skin symptoms (pain, itch, tightness), physical limitations and treatment burden
Original publication
Systematic Review of Health‐Related Quality of Life Impact in Juvenile Localized Scleroderma. Arthritis Care Res (Hoboken). Published 7 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →