Clinical Features and Outcome Measures Across Still Disease (Systemic Juvenile Idiopathic Arthritis and Adult-Onset Still Disease) Cohorts Worldwide: A Systematic Literature Review
An erratum to this article was published (J Rheumatol, 1 Aug 2026 ↗)
Authors' conclusion
Data reporting across sJIA and AOSD cohorts for clinical characteristics and outcome measures is widely heterogeneous.
Study context
- Population
- Systemic juvenile idiopathic arthritis (sJIA) or Adult-onset Still disease (AOSD) cohorts of ≥ 20 patients, English-language articles 2000–2024240 articles
- Participants
- 23,136 participants37 countries
- Comparison
- sJIA vs AOSD
- Outcome
- Clinical features and outcome measures collected across sJIA and AOSD cohorts worldwide
Main finding
As reported in the abstract
Clinical features and outcome measures reported across cohorts
Articles included: 95 sJIA, 134 AOSD, 11 mixed
240
sJIA studies using International League of Associations for Rheumatology classification
77.9%
AOSD studies using Yamaguchi criteria
98.5%
Articles reporting race and ethnicity
11.7%
Original publication
Clinical Features and Outcome Measures Across Still Disease (Systemic Juvenile Idiopathic Arthritis and Adult-Onset Still Disease) Cohorts Worldwide: A Systematic Literature Review. J Rheumatol. Published 1 October 2025. doi:10.
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