Childhood-onset Takayasu arteritis: clinical presentation, challenges and disease course
Authors' conclusion
Children with TAK often experience a complex disease course requiring multiple treatment adjustments and surgical or endovascular interventions.
Study context
- Population
- Children under 18 years at onset with c-TAK meeting EULAR/PRINTO/PReS criteria, Alberta Children's Hospital, Calgary, Canada, 2000–20244 female
- Participants
- 6 participants
- Outcome
- Clinical presentation, affected arteries and treatment
Methodological detailssingle-centre, tertiary centre
- Single-centre
- Tertiary centre
Main finding
As reported in the abstract
- Median age at diagnosis, years (range 4-17)
- 14.5
- Fatigue
- n = 4
- Weight loss
- n = 3
- Hypertension
- n = 3
- Abdominal aorta and carotid arteries affected
- n = 5
- Ascending aorta affected
- n = 4
- Corticosteroids for induction
- All patients
- MTX
- n = 5
- Infliximab
- n = 2
- Tocilizumab
- n = 2
- IVIG
- n = 2
- Etanercept
- n = 1
- Adalimumab
- n = 1
- CYC
- n = 1
Observational data: associations, not effects.
Original publication
Childhood-onset Takayasu arteritis: clinical presentation, challenges and disease course. Pediatr Rheumatol Online J. Published 29 September 2025. doi:10.
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