Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening
Authors' conclusion
A large-scale outpatient screening of AYA with JIA in Germany shows a high prevalence of anxiety and depression symptoms.
Study context
- Population
- Outpatients aged 12 to 21 years with juvenile idiopathic arthritis (JIA) participating in the National Pediatric Rheumatological Database (NPRD), Germanyanalysed
- Participants
- 1,150 outpatients
- Exposure
- Conspicuous vs inconspicuous screening results
- Conspicuous screeningn = 316
- Outcome
- Prevalence of anxiety and depression symptoms (PHQ-9 and GAD-7 screening)
Methodological detailsmulticentre, prospective outpatient screening, part of the COACH observational study
- Multicentre
- Prospective outpatient screening
- Part of the COACH observational study
Main finding
As reported in the abstract
Conspicuous screening result (anxiety/depression symptoms)
And young adults (AYA) with conspicuous screening results
32.7%
n = 316
Clinically relevant suicidal or self-harm thoughts among those with conspicuous results
30.4%
Moderate to severe depressive or anxious symptoms
About 19%
Observational data: associations, not effects.
Further findings
Characteristics, conspicuous vs inconspicuous
P < 0.0001
Characteristics, conspicuous vs inconspicuous
P = 0.006
Factors associated with conspicuous screening result
| OR (CI) | P value | ||
|---|---|---|---|
| Female | 2.33 (1.53–3.56) | P < 0.0001 | |
| Older age | 1.09 (1.01–1.18) | P = 0.026 | |
| More functional limitations | 3.36 (1.98–5.72) | P < 0.0001 | |
| Worse subjective health status | 1.17 (1.07–1.27) | P < 0.0001 | |
| Regular sports participation | 0.69 (0.49–0.98) | P = 0.039 | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | Conspicuous screening | Inconspicuous screening | P value |
|---|---|---|---|
| Characteristics, conspicuous vs inconspicuous15.8 vs. 15.2 years | P < 0.0001 | ||
| Characteristics, conspicuous vs inconspicuous | 1.7 | 1.2 | P < 0.0001 |
| Characteristics, conspicuous vs inconspicuous | 0.44 | 0.14 | <0.0001 |
| Characteristics, conspicuous vs inconspicuous | 3.5 | 1.8 | P < 0.0001 |
Original publication
Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening. Arthritis Res Ther. Published 10 April 2024. doi:10.
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