Multicenter Study of Utility and Acceptability of Depression and Anxiety Screening in Adolescents and Young Adults With Childhood‐Onset Systemic Lupus
Authors' conclusion
Depression, anxiety, and suicidal ideation are common among AYA with cSLE, and symptoms are correlated with important patient-reported outcomes. Mental health screening in the pediatric rheumatology setting was highly acceptable among AYA with cSLE and their parents.
Study context
- Population
- And young adults (AYA) aged 12–21 years with childhood-onset SLE (cSLE), 8 pediatric rheumatology sites
- Participants
- 106 participants8 sites
- Outcome
- Utility and acceptability of depression and anxiety screening (PHQ-9, GAD-7)
Methodological detailsmulticentre, consecutive screening
- Multicentre
- Consecutive screening
Main finding
As reported in the abstract
Positive screen (PHQ-9/GAD-7)
- Screened positive (any)
- 32 (30%)
- Positive for depression
- 24%
- Positive for anxiety
- 17%
- Positive for suicidal ideation
- 14%
- AYA comfortable with screening in pediatric rheumatology setting
- 86%
- Parents comfortable with screening in pediatric rheumatology setting
- 95%
Observational data: associations, not effects.
Further findings
Previous screening
- Previously screened
- 64 (60%)
- Previously screened by general pediatricians
- 25 (24%)
Correlation of depression/anxiety severity with Patient Reported Outcomes Measurement Information System (PROMIS) domains
- Highly correlated with increased PROMIS fatigue and pain interference
- Moderately correlated with increased pain severity, decreased mobility and decreased peer relationships
- Spearman correlations
Original publication
Multicenter Study of Utility and Acceptability of Depression and Anxiety Screening in Adolescents and Young Adults With Childhood‐Onset Systemic Lupus. Arthritis Care Res (Hoboken). Published 23 December 2022. doi:10.
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