Sjögren's disease & overlap diseases
Real-World Diagnostic Performance of OMERACT Salivary Gland Ultrasound in Patients Evaluated for Sicca Symptoms
Authors' conclusion
In real-world settings, SGUS using the OMERACT score demonstrates high specificity, particularly in PGs, and moderate sensitivity, outperforming UWSFR in younger patients.
Study context
- Population
- Consecutive outpatients referred for dryness evaluation (suspected sjögren disease (SjD))51 fulfilled ACR/EULAR criteria
- Participants
- 103 outpatients
- Comparison
- OMERACT salivary gland ultrasound (SGUS) vs salivary flow and Schirmer test, against 2016 ACR/EULAR criteria
- Outcome
- Diagnostic accuracy of OMERACT SGUS vs 2016 ACR/EULAR criteria
Methodological detailsprospective, consecutive outpatients, two blinded sonographers
- Prospective
- Consecutive outpatients
- Two blinded sonographers
Performance
As reported in the abstract
Diagnostic performance
| Test or model | Sensitivity | Specificity |
|---|---|---|
| SGUS | 66.7% | 76.9% |
| PG | 49% | 92.3% |
| SMG | 58.8% | 78.8% |
| Schirmer test | 49% | — not stated in the abstract |
| Unstimulated whole salivary flow rate (UWSFR) | 52.9% | — not stated in the abstract |
| Stimulated whole salivary flow rate | 17.6% | 94.2% |
Sensitivity
SGUS66.7%
PG49%
SMG58.8%
Schirmer test49%
Unstimulated whole salivary flow rate (UWSFR)52.9%
Stimulated whole salivary flow rate17.6%
Specificity
SGUS76.9%
PG92.3%
SMG78.8%
Schirmer test— not stated in the abstract
Unstimulated whole salivary flow rate (UWSFR)— not stated in the abstract
Stimulated whole salivary flow rate94.2%
— not stated in the abstract
Further findings
| Outcome | Values |
|---|---|
| Sensitivity by age (subgroup) | UWSFR sensitivity, age < 40 years 20% · sensitivity, age ≥ 40 years 57.1% |
Sensitivity by age (subgroup)
- SGUS maintained stable performance in patients aged < 40 years
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Real-World Diagnostic Performance of OMERACT Salivary Gland Ultrasound in Patients Evaluated for Sicca Symptoms. J Rheumatol. Published 1 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →