Systemic sclerosis & Raynaud's

Racial and ethnic associations with interstitial lung disease and healthcare utilization in patients with systemic sclerosis

Rheumatology (Oxford)Published Retrospective cohort study

Main finding · ILD codeResult — go to the resultOdds ratio 2.60 95% CI 1.29–5.28

Authors' conclusion

We found that odds of SSc-ILD differed by racial/ethnic group; minoritized patients had earlier age of presentation and greater rates of an ED visit.

Study context

Population
Patients with SSc in an integrated health-system
Participants
756 patients
Exposure
Racial/ethnic groups vs White patients
Outcome
ILD (ILD code)
Methodological detailsintegrated health-system longitudinal health records, logistic regression, complementary log-log regression
  • Integrated health-system longitudinal health records
  • Logistic regression
  • Complementary log-log regression

Main finding

ILD code

Odds ratio

2.60

95% CI 1.29–5.28

P = 0.008

Asianvs White
OR 2.60 (95% CI 1.29–5.28); P = 0.008

As reported in the abstract

Patients in the cohort with an ILD code
33.7%

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
ED visit rateBlack/African Americanvs White2.59 (1.47–4.49)P = 0.001
ED visit rateHispanicvs White2.29 (1.37–3.82)P = 0.002
OutcomeBlack/African AmericanWhiteEstimate (years) (95% CI)P value
Predicted age at SSc-ILDHispanic vs White · younger−6.5 (−13 to −0.21)P = 0.04
Predicted age at SSc-ILDBlack/African American vs White · younger−10 (−16 to −4.9)P < 0.001
ILD code before SSc code59%20.6%
ILD code before SSc code — Shortest interval from SSc to ILD in Black/African American patients
3 months

Original publication

Racial and ethnic associations with interstitial lung disease and healthcare utilization in patients with systemic sclerosis. Rheumatology (Oxford). Published 9 August 2024. doi:10.1093/rheumatology/keae430

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