Lupus & antiphospholipid syndrome
Qualitative interview study in patients with SLE to assess patient perception of fatigue and skin-related symptoms
Authors' conclusion
These results support the use of the FACIT-Fatigue scale in SLE trials and suggest that even minimal improvements in fatigue and skin symptoms are meaningful to patients.
Study context
- Population
- Adults in the USA with self-reported SLE and SLE-related fatigue within the prior 30 days17 with skin symptoms
- Participants
- 18 adults
- Outcome
- Content validity of the FACIT-Fatigue scale for SLE-related fatigue and smallest meaningful improvement in fatigue and skin symptoms (PGIS, PGIC)
Methodological detailsindividual interviews conducted virtually, cognitive debriefing, 60 min individual interviews conducted virtually in August 2023
- Individual interviews conducted virtually
- Cognitive debriefing
- 60 min individual interviews conducted virtually in August 2023
Main finding
As reported in the abstract
- Participants indicating a one-point improvement in fatigue on the Patient Global Impression of Severity (PGIS) would be meaningful
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Original publication
Qualitative interview study in patients with SLE to assess patient perception of fatigue and skin-related symptoms. Lupus Sci Med. Published 7 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →