Lupus & antiphospholipid syndrome
Association of systemic lupus erythematosus with 90-day readmission following heart failure hospitalization: A national readmission database (NRD) analysis, 2016–2017
Main finding · 90-days readmissionResult — go to the resultHazard ratio 1.07 95% CI 1.02–1.12Authors' conclusion
Systemic lupus erythematosus is independently associated with an increased risk of 90-days readmission following heart failure hospitalization, contributing to greater healthcare utilization and costs.
Study context
- Population
- Adults ≥18 years with an index admission for HF, Nationwide Readmissions Database 2016–20179,096 with SLE
- Participants
- 1,625,731 adults
- Exposure
- SLE vs non-SLE among patients hospitalised with HF
- SLEn = 9,096
- Outcome
- 90-days all-cause readmission
- Follow-up
- 90 days
Methodological detailsNationwide Readmissions Database 2016-2017, multivariable Cox proportional hazards
- Nationwide Readmissions Database 2016-2017
- Multivariable Cox proportional hazards
Main finding
90-days readmission
Hazard ratio
1.07
95% CI 1.02–1.12
P = 0.010
By group
SLEvs Non-SLE
HR 1.07 (95% CI 1.02–1.12); P = 0.010
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | SLE | Non-SLE |
|---|---|---|
| Median LOS | median 4 days | 4 days |
| Median hospitalization costs | median 32,872 USD | — not stated in the abstract |
— not stated in the abstract
In-hospital mortality
- In-hospital mortality did not differ significantly between groups
Mortality during readmissions vs index admissions
- Mortality during readmissions
- 5.4%
- Mortality during index admissions
- 2.9%
- Nearly doubled compared with index admissions
Median hospitalization costs
- SLE costs 13% higher than non-SLE patients
Original publication
Association of systemic lupus erythematosus with 90-day readmission following heart failure hospitalization: A national readmission database (NRD) analysis, 2016–2017. Lupus. Published 4 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →