Lupus & antiphospholipid syndrome
Outcomes of systemic lupus erythematosus hospitalisations in Qatar: Insights from a multinational tertiary centre experience
Authors' conclusion
In this multinational cohort, SLE flares and infections were the leading causes of hospitalisation. Sepsis, comorbid conditions, and high disease activity are associated with adverse outcomes.
Study context
- Population
- Adults (aged ≥18 years) with SLE hospitalised at Hamad General Hospital, Qatar, June 2016–August 2020; multinational cohort
- Participants
- 153 adults281 admissions
- Exposure
- Intensive care unit (ICU) admission vs no ICU admission
- Outcome
- Causes, clinical course and outcomes of hospitalisations among patients with SLE
Methodological detailssingle-centre, univariable and multivariable logistic regression
- Single-centre
- Univariable and multivariable logistic regression
Main finding
As reported in the abstract
- Lupus flare, haematologic
- 38%
- Lupus flare, renal
- 28%
- Lupus flare, articular
- 20%
- Infection
- 20%
- Median hospital stay, days (IQR 4-12)
- 7
- Re-admission (of patients)
- 51%
- Admissions requiring ICU care
- 17%
Observational data: associations, not effects.
Further findings
Hospital stay (median days), ICU vs non-ICU
P < 0.001
Mortality, ICU vs non-ICU
P < 0.001
Predictors of ICU admission (multivariable logistic regression)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Higher SLEDAI score | 1.14 (1.07–1.21) | P < 0.001 | |
| Sepsis | 4.91 (2.02–11.89) | P < 0.001 | |
| Cardiac involvement | 7.57 (1.74–32.93) | P = 0.007 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Outcomes of systemic lupus erythematosus hospitalisations in Qatar: Insights from a multinational tertiary centre experience. Lupus. Published 11 June 2026. doi:10.
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