Lupus & antiphospholipid syndrome
Psychiatric comorbidities in patients suffering from systemic lupus erythematosus admitted to a tertiary care hospital in Northern India
Authors' conclusion
Patients with SLE have a high prevalence of psychiatric comorbidities and should be routinely screened for psychiatric morbidity.
Study context
- Population
- Patients with Systemic Lupus Erythematosus (SLE) for at least 1 year, not in delirium, admitted to a tertiary care hospital in Northern India
- Participants
- 79 patients
- Outcome
- Prevalence of psychiatric disorders per ICD-10 criteria, assessed by a qualified psychiatrist
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Any psychiatric diagnosis (ICD-10)
- Any psychiatric diagnosis
- 51% (n = 40)
- Depressive disorders (most common)
- 36.7% (n = 29)
- Adjustment disorder
- 10% (n = 8)
- Anxiety (not otherwise specified)
- 2.5% (n = 2)
- Organic psychosis
- 1 patient
Observational data: associations, not effects.
Further findings
Screening and cognitive scales (PHQ-9, PHQ-15, GAD-7, Montreal Cognitive Assessment (MoCA))
- Depression on PHQ-9
- 39.8% (n = 33)
- Death wishes and/or suicidal ideations
- 44.3% (n = 35)
- Severe somatic distress on PHQ-15 (score >15)
- 17.7% (n = 14)
- Positive screen for anxiety symptoms on GAD-7
- 55.7% (n = 44)
- Severe anxiety on GAD-7 (score of 15 or more)
- 7.6%
- Cognitive impairment on MoCA
- 52% (n = 43)
- Scores indicating severe dementia on MoCA
- 13.3% (n = 11)
- Count for severe anxiety not printed ("n = ")
Original publication
Psychiatric comorbidities in patients suffering from systemic lupus erythematosus admitted to a tertiary care hospital in Northern India. Lupus. Published 19 May 2023. doi:10.
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