Lupus & antiphospholipid syndrome

Prevalence of pulmonary diseases among patients newly diagnosed with systemic lupus erythematosus: A cross-sectional case-series introducing thoracic ultrasound and diaphragmatic ultrasound

LupusPublished Cross-sectional study

Authors' conclusion

We found PD among newly diagnosed patients with SLE and in some cases associated with severely affected pulmonary function.

Study context

Population
Patients newly diagnosed with Systemic Lupus Erythematosus (SLE), 1 July 2023 to 31 July 2024, Odense University Hospital, Denmarkincluded avg 3 months after SLE diagnosis
Participants
10 patients
Outcome
Presence of pulmonary diseases (PD) and PD subtypes, diagnosed on multidisciplinary discussion
Methodological detailscase series, single-centre
  • Case series
  • Single-centre

Main finding

As reported in the abstract

Pulmonary diseases (PD)

Participants with PD

6 of 10

Shrinking lung syndrome (SLS)

1

ILD

2

Observational data: associations, not effects.

Further findings

Pulmonary function tests (PFT)

Participants with ≥1 abnormal PFT measure
10 of 10
Some with severely reduced pulmonary function

Thoracic US (thoracic ultrasound (TUS)) and diaphragmatic US (diaphragmatic ultrasound (DUS))

TUS associated with diseases of lung parenchyma and pleura; DUS with SLS

Original publication

Prevalence of pulmonary diseases among patients newly diagnosed with systemic lupus erythematosus: A cross-sectional case-series introducing thoracic ultrasound and diaphragmatic ultrasound. Lupus. Published 7 December 2025. doi:10.1177/09612033251406325

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