Lupus & antiphospholipid syndrome

Pulmonary diseases in SLE: a population-based cross-sectional study

Lupus Sci MedPublished Cross-sectional study

Authors' conclusion

59% of patients with SLE have PD, and PD was associated with decreased pulmonary function.

Study context

Population
Adult patients with SLE meeting classification criteria, Region Southern Denmark
Participants
185 patients
Outcome
Prevalence of pulmonary disease (PD) in SLE
Methodological detailspopulation-based
  • Population-based

Main finding

As reported in the abstract

Prevalence of PD

PD prevalent

109

59%

Observational data: associations, not effects.

Secondary outcomes

Prevalence of PD subtypes

ILD
22 (12%)
Pleural diseases
35 (19%)
Airway diseases
70 (38%)

Pulmonary function

PD and subtypes of PD associated with decreased pulmonary function; PFT measures showed low combined sensitivity and specificity for detecting PD and subtypes

Associations of patient characteristics with PD

No strong associations between selected patient characteristics and presence of PD or subtypes of PD

Original publication

Pulmonary diseases in SLE: a population-based cross-sectional study. Lupus Sci Med. Published 31 March 2026. doi:10.1136/lupus-2025-001895

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