Vasculitis & polymyalgia rheumatica
Pregnancy outcome in patients with a medical history of immunoglobulin A vasculitis: a case–control study
Authors' conclusion
Women with a history of IgA-V appear to be at higher risk for gestational hypertension and pre-eclampsia, especially in cases with renal involvement; however, both mother and newborn outcomes appear to be favourable.
Study context
- Population
- Pregnancies in women with a history of IgAV, Francepregnancies
- Participants
- 26 / 15 / 52
- Comparison
- Pregnancies in women with a history of IgAV vs pregnancies in women who later developed IgAV vs pregnancies in healthy women
- Casesn = 26
- Later IgAVn = 15
- Healthy controlsn = 52reference
- Outcome
- Maternal, neonatal and vasculitis outcomes during pregnancy
Methodological detailsFrench
- French
Further findings
Gestational hypertension · during pregnancy · case group vs the other groups
P < 0.01
Pre-eclampsia · during pregnancy · case group vs the other groups
P = 0.04
Caesarean section · case group vs the other groups
P = 0.04
Hypertensive disorder of pregnancy, pre-existing kidney disease vs not (subgroup)
- More frequent with pre-existing kidney disease (78% vs 12%, p < 0.01)
Delivery term and birth weight
- There were no differences in delivery term or birth weight
Vasculitis flares · during pregnancy
- No vasculitis flares were observed during pregnancy
Safety
Foetal loss and maternal deaths
- None occurred
- 0
Original publication
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