Vasculitis & polymyalgia rheumatica
Treatment strategies and outcomes in adult relapsing or refractory cutaneous IgA Vasculitis: A multicenter retrospective cohort study
Authors' conclusion
In adult relapsing or refractory cutaneous IgA vasculitis, dapsone, GCs and cDMARDs provided the highest rates of cutaneous response.
Study context
- Population
- Adults with IgAV with cutaneous relapses or refractory disease after first-line therapy, France64% male
- Participants
- 52 adults
- Exposure
- Second-line treatment regimens after failure of first-line therapy
- Outcome
- Rate of cutaneous response
- Follow-up
- Month 3
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Cutaneous response · 3 months
Observational data: associations, not effects.
Further findings
Relapse rate
Additional lines of treatment after first-line failure
- Median additional lines of treatment [1-2.3]
- 1
- First-line: colchicine 54%, low-dose glucocorticoids (GCs) 38%
Original publication
Treatment strategies and outcomes in adult relapsing or refractory cutaneous IgA Vasculitis: A multicenter retrospective cohort study. Semin Arthritis Rheum. Published 6 November 2025. doi:10. 1016/ j. semarthrit. 2025. 152870
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