Lupus & antiphospholipid syndrome

Predictors of Thirty‐Day Hospital Readmissions in Systemic Lupus Erythematosus in the United States: A Nationwide Study

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Authors' conclusion

In this nationally representative study of SLE readmissions, the strongest risk factors for 30-day readmission were younger age, SLE-related manifestations, and public insurance.

Study context

Population
Adults with systemic lupus erythematosus (SLE) discharged from hospital to home, January-November 2016 and 2017, United States88.3% female
Participants
132,400 adults
Outcome
30-day all-cause readmission
Follow-up
30 days
Methodological detailsnationally representative, Nationwide Readmissions Database, multivariable adjusted survey-specific logistic regression
  • Nationally representative
  • Nationwide Readmissions Database
  • Multivariable adjusted survey-specific logistic regression

Main finding

As reported in the abstract

30 days after discharge
Odds ratio (95% CI)
Autoimmune hemolytic anemia
1.86(1.51–2.29)
Glomerular disease
1.27(1.19–1.36)
Pericarditis
1.35(1.14–1.60)
HF
1.34(1.24–1.44)
Age 18-30 yearsvs Age ≥65 years
1.28(1.17–1.41)
Medicare
1.20(1.13–1.28)
Medicaid insurance
1.26(1.18–1.34)
Readmitted within 30 days of discharge from index hospitalization
18,973 (14.3%)

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)
Factors associated with readmission (multivariable) · 30 daysAge 18-30 yearsvs Age ≥​65 years1.28 (1.17–1.41)

Factors associated with readmission (multivariable) · 30 days

OR (95% CI)
Medicaid1.26 (1.18–1.34)

Most common causes of readmission

Sepsis
7.6%
SLE
7.4%
HF
3.5%
Pneumonia
3.2%

Original publication

Predictors of Thirty‐Day Hospital Readmissions in Systemic Lupus Erythematosus in the United States: A Nationwide Study. Arthritis Care Res (Hoboken). Published 8 December 2022. doi:10.1002/acr.24900

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