Spondyloarthritis & psoriatic arthritis

Patient-tailored training programme on cardiorespiratory fitness, trunk strength and mobility leads to significantly better outcomes in individuals with axial spondyloarthritis

RMD OpenPublished Prospective interventional study

Authors' conclusion

A combined, tailored and baseline-guided training programme significantly enhanced cardiorespiratory fitness, trunk strength and trunk mobility in individuals with axSpA

Study context

Population
People with axial spondyloarthritis (axSpA) (14 males/16 females, age 42±11.2 years)two lost to follow-up
Participants
30 people
Exposure
Personalised 8-week combined cardiorespiratory and trunk resistance/mobility training, pre vs post
  • axSpAn = 30
Outcome
Trunk strength, mobility and cardiorespiratory fitness, pre vs post
Follow-up
8 weeks
Methodological detailssingle-group, pre-post, linear mixed models
  • Single-group
  • Pre-post
  • Linear mixed models

Main finding

As reported in the abstract

Strength increased
14.1% (p<0.001)
Mobility increased
14.9% (p<0.001)
Oxygen pulse, significant improvement
p=0.004
Ventilatory efficiency, significant improvement
p<0.001
Anaerobic threshold, significant improvement
p=0.002
Mechanical efficiency, significant improvement
p=0.021

Observational data: associations, not effects.

Further findings

Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), post-intervention · 8 weeks

BASDAI post-intervention (mean±SD; baseline 3.5±2.1), improved significantly
2.9±2.2, p=0.021

Chest expansion (CE), post-intervention · 8 weeks

CE post-intervention (baseline 4.5±2.0 cm), improved significantly
5.0±2.1, p=0.020

Bath Ankylosing Spondylitis Metrology Index (BASMI), post-intervention · 8 weeks

BASMI post-intervention (baseline 2.0±1.1), borderline improvement
1.8±1.0, p=0.053

Bath Ankylosing Spondylitis Functional Index (BASFI), post-intervention · 8 weeks

BASFI post-intervention (baseline 2.8±2.2), remained unchanged
2.4±2.1, p=0.092

Cardiopulmonary exercise testing (CPET) parameters · 8 weeks

Oxygen pulse, significant improvement
P = 0.004
Ventilatory efficiency, significant improvement
P < 0.001
Anaerobic threshold, significant improvement
P = 0.002
Mechanical efficiency, significant improvement
P = 0.021

Original publication

Patient-tailored training programme on cardiorespiratory fitness, trunk strength and mobility leads to significantly better outcomes in individuals with axial spondyloarthritis. RMD Open. Published 31 December 2025. doi:10.1136/rmdopen-2025-006039

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