Spondyloarthritis & psoriatic arthritis

Maximal Exercise Tolerance, Objective Trunk Strength, and Mobility Measurements in Axial Spondyloarthritis

J RheumatolPublished Cross-sectional study

Authors' conclusion

In patients with axSpA, strength is more affected than mobility when compared to healthy controls. Likewise, mainly the metabolic component of aerobic capacity is impaired, affecting cardiopulmonary fitness.

Study context

Population
Patients with axial spondyloarthritis (axSpA) (mean age 40.8 yrs, 50% male, mean symptom duration 10.3 yrs)CPET in 25
Participants
58 patients
Exposure
axSpA vs healthy reference data; radiographic vs nonradiographic axSpA
  • axSpAn = 58
Outcome
Trunk strength, spinal mobility and cardiorespiratory fitness
Methodological detailscomparison with healthy reference data
  • Comparison with healthy reference data

Main finding

As reported in the abstract

Strength significantly lower in axSpA vs reference
P ≤ 0.02
Mobility significantly lower in axSpA vs reference
P ≤ 0.001

Observational data: associations, not effects.

Further findings

Radiographic vs nonradiographic axSpA

Strength deficits comparable between radiographic and nonradiographic groups
P > 0.05
Except trunk extension strength
P = 0.03
Higher mobility deficit in radiographic group: cervical extension
P = 0.02
Higher mobility deficit in radiographic group: cervical rotation
P = 0.01
Higher mobility deficit in radiographic group: trunk extension
P = 0.03
Higher mobility deficit in radiographic group: trunk rotation
P = 0.03
  • Regardless of symptom duration

Effect of symptom duration on cardiopulmonary variables

Symptom duration positively affected oxygen pulse
P = 0.03
Symptom duration positively affected relative anaerobic threshold
P = 0.02
Symptom duration positively affected aerobic capacity
P = 0.02

Original publication

Maximal Exercise Tolerance, Objective Trunk Strength, and Mobility Measurements in Axial Spondyloarthritis. J Rheumatol. Published 15 March 2024. doi:10.3899/jrheum.2023-1046

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