Spondyloarthritis & psoriatic arthritis
Clinical Field Tests to Evaluate Cardiorespiratory Fitness in Psoriatic Arthritis
Authors' conclusion
6MWD was strongly associated with VO2peak, was moderately to strongly correlated with important clinical outcomes, and had adequate accuracy to detect patients with impaired CRF.
Study context
- Population
- Patients with PsA
- Participants
- 80 patients
- Exposure
- Clinical field tests vs VO2peak by cardiopulmonary exercise testing
- Outcome
- Associations of 6MWD and HGS with cardiorespiratory fitness (CRF) (VO2peak, mL/min/kg) and accuracy in detecting impaired CRF
Methodological detailscardiopulmonary exercise testing, Spearman correlation, multivariable linear regression, ROC analysis
- Cardiopulmonary exercise testing
- Spearman correlation
- Multivariable linear regression
- ROC analysis
Main finding
As reported in the abstract
| Group | rS with VO2peak | Sensitivity (threshold 108% predicted 6MWD) | Specificity (threshold 108% predicted 6MWD) |
|---|---|---|---|
| 6MWD | 0.65 | 75% | 64% |
6MWD
rS with VO2peak0.65
Sensitivity (threshold 108% predicted 6MWD)75%
Specificity (threshold 108% predicted 6MWD)64%
- 6MWD strongly associated with VO2peak, P < 0.001
- 0.65
Observational data: associations, not effects.
Further findings
6MWD and handgrip strength (HGS) vs general population reference charts
- 6MWD and HGS not significantly decreased vs general population (P > 0.05)
- One-sided t-tests
Correlation with clinical outcomes
- Higher 6MWD moderately to strongly correlated with more favorable disease activity, cardiometabolic risk and patient-reported outcomes
- No or only weak associations between HGS and clinical outcomes
Original publication
Clinical Field Tests to Evaluate Cardiorespiratory Fitness in Psoriatic Arthritis. Arthritis Care Res (Hoboken). Published 17 August 2026. doi:10. 1002/ acr. 80138
Composed by AI from the published abstract and checked against it. How Briefs are made →