Lupus & antiphospholipid syndrome

Lupus nephritis and socioeconomic status: Findings from the Southern California lupus registry

LupusPublished Registry-based cohort study

Authors' conclusion

Low SES, when defined by insurance, is associated with greater adverse outcomes in SLE.

Study context

Population
All-comers with Systemic Lupus Erythematosus (SLE) in the Southern California Lupus Registry (SCOLR)35 patients analysed for SLE disease activity index (SLEDAI)
Exposure
Public vs private insurance
Outcome
Association between SES (insurance, ethnicity) and LN
Methodological detailsadjusted for age and sex
  • Adjusted for age and sex

Main finding

As reported in the abstract

Prevalence of LN
  • Public insurance independently associated with prevalence of lupus nephritis (LN) after adjusting for age and sex

Observational data: associations, not effects.

Further findings

Proteinuria and mean SLEDAI by insurance · Baseline and 6 months

Greater proteinuria and mean SLEDAI with public insurance

Mean SLEDAI by ethnicity · Baseline, 6 and 12 months

Significantly lower in Asian/PI vs others

Change in mean SLEDAI over 6 months by ethnicity

Improvement in non-Hispanic Whites; worsened on average in Asians/PI, Blacks and Hispanics

Original publication

Lupus nephritis and socioeconomic status: Findings from the Southern California lupus registry. Lupus. Published 10 January 2024. doi:10.1177/09612033241227035

Composed by AI from the published abstract and checked against it. How Briefs are made →

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