Lupus & antiphospholipid syndrome
Systemic lupus erythematosus is associated with increased risk of mortality and acute kidney injury in patients with COVID-19 hospitalization: Insights from a National Inpatient Sample analysis
Authors' conclusion
COVID-19 patients with SLE are at an increased mortality risk, especially in the younger age group, and a higher incidence of acute kidney injury requiring dialysis.
Study context
- Population
- COVID-19 hospitalizations in the National Inpatient Sample (NIS)over a million hospitalizations
- Exposure
- COVID-19 hospitalizations with systemic lupus erythematosus (SLE) vs without SLE
- Outcome
- In-hospital mortality
Methodological detailspropensity-score matched, National Inpatient Sample
- Propensity-score matched
- National Inpatient Sample
Main finding
As reported in the abstract
- In-hospital mortality higher in the SLE group
- Propensity-score matched
Observational data: associations, not effects.
Further findings
In-hospital mortality, age 18-44 years (subgroup)
- In-hospital mortality higher in SLE vs non-SLE, age 18-44 years
- 6.15% vs 2.47%, p = .022
Original publication
Systemic lupus erythematosus is associated with increased risk of mortality and acute kidney injury in patients with COVID-19 hospitalization: Insights from a National Inpatient Sample analysis. Lupus. Published 9 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →