Osteoarthritis

Influence of Self‐Reported Knee Instability on Outcomes Following Education and Exercise: A Cohort Study of 2,466 Patients With Knee Osteoarthritis

Arthritis Care Res (Hoboken)Published Cohort study

Main finding · Change in knee pain (0-100 mm)Result — go to the resultLarger improvement in pain 4.3 mm 95% CI 1.2–7.5

Authors' conclusion

Knee OA patients with self-reported instability seem to benefit even more from a patient education and supervised exercise therapy program than OA patients without instability.

Study context

Population
Patients with knee osteoarthritis (OA) in the GLA:D program (8-week education and supervised neuromuscular exercise), Denmark
Participants
2,466 patients
Exposure
Self-reported knee instability categories vs no instability
Outcome
Change in knee pain intensity (0-100 mm) and gait speed (4 × 10 m fast-paced walk test)
Follow-up
After the program
Methodological detailslinear regression, adjusted for sex, age, BMI, physical activity level and previous knee surgery
  • Linear regression
  • Adjusted for sex, age, BMI, physical activity level and previous knee surgery

Main finding

Change in knee pain (0-100 mm)

Larger improvement in pain

4.3 mm

95% CI 1.2–7.5

As reported in the abstract

Observational data: associations, not effects.

Further findings

Baseline mean pain and gait speed, no instability vs instability most or all the time

Mean baseline pain range (mm)
38-59
Mean baseline gait speed range (meters/second)
1.39-1.56

Original publication

Influence of Self‐Reported Knee Instability on Outcomes Following Education and Exercise: A Cohort Study of 2,466 Patients With Knee Osteoarthritis. Arthritis Care Res (Hoboken). Published 14 January 2023. doi:10.1002/acr.25060

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