GLA:D to Be Walking Better: Change in Self-Reported Difficulty Walking After Exercise Therapy and Education in Persons With Knee Osteoarthritis
Authors' conclusion
More than half of those with baseline difficulty walking experienced substantial improvement after completing GLA:D and this improvement was maintained at 12 months.
Study context
- Population
- Individuals in Denmark with knee osteoarthritis (OA) enrolled in the GLA:D 8-week education and exercise program
- Participants
- 5,262 individuals
- Outcome
- Change in self-reported difficulty walking (EuroQol 5-dimension 5-level walking item)
- Follow-up
- ≈3 months and 12 months
Methodological detailsprespecified primary outcome, multivariable regression analysis
- Prespecified primary outcome
- Multivariable regression analysis
Main finding
As reported in the abstract
No/slight difficulty walking among those with baseline moderate/severe difficulty walking (n = 2178, 41.4%) · 3 and 12 months
No/slight difficulty walking at 3 months
51.4%
No/slight difficulty walking at 12 months
58.3%
Observational data: associations, not effects.
Further findings
Patient factors associated with improvement to no/slight difficulty walking
- Greater self-efficacy, younger age, female sex, lower BMI, less intense knee pain and better function at baseline associated with greater likelihood of improvement
- Severe difficulty walking at baseline and back pain intensity associated with decreased likelihood of improvement
Original publication
GLA:D to Be Walking Better: Change in Self-Reported Difficulty Walking After Exercise Therapy and Education in Persons With Knee Osteoarthritis. J Rheumatol. Published 15 June 2024. doi:10.
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