Osteoarthritis

Factors Influencing Pain Response Following Patient Education and Supervised Exercise in Male and Female Subjects With Hip Osteoarthritis

Arthritis Care Res (Hoboken)Published Cohort study

Authors' conclusion

Findings suggest that the influence of some factors on pain response differ for male and female subjects

Study context

Population
Individuals with hip osteoarthritis (OA) participating in the Danish Good Life With Osteoarthritis in Denmark 8-week education and exercise program
Participants
2,253 vs 791
Exposure
Women vs men
  • Womenn = 2,253
  • Menn = 791reference
Outcome
Pain responder: pain intensity (0-100-mm VAS) improvement of ≥30% from baseline to post-program
Follow-up
Month 3 (post-program)
Methodological detailsregistry data from GLA:D education and exercise program, logistic regression, separately by sex
  • Registry data from GLA:D education and exercise program
  • Logistic regression, separately by sex

Main finding

As reported in the abstract

Proportion of pain responders · post-program

P = 0.025

Observational data: associations, not effects.

Further findings

Mean

OutcomeWomenMen
Baseline pain score (0-100) · mean baseline47.2 (95% CI 46.4–48.1)41.7 (95% CI 40.3–43.1)

Factors associated with pain response in women · post-program

Attending former participant lectures and more supervised exercise sessions, better mental well-being and fewer comorbidities positively associated with response; symptoms in other joints/sites associated with decreased likelihood of response

Factors associated with pain response in men · post-program

Program-specific factors not associated with response; better mental well-being and fewer comorbidities associated with being a responder

Original publication

Factors Influencing Pain Response Following Patient Education and Supervised Exercise in Male and Female Subjects With Hip Osteoarthritis. Arthritis Care Res (Hoboken). Published 10 January 2023. doi:10.1002/acr.24954

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