Lupus & antiphospholipid syndrome

Impact of telemedicine on disease activity assessment: A case-crossover study nested within a cohort of patients with systemic lupus erythematosus

LupusPublished Case-crossover study nested within a prospective cohort

Main finding · SLEDAI-2K scoreResult — go to the resultMean difference −1.641 95% CI −2.773 to −0.510

Authors' conclusion

We found that telemedicine assessment was associated with a much higher disease activity score than subsequent assessments, which may suggest an overestimation of disease activity and later assessment accuracy.

Study context

Population
Patients with systemic lupus erythematosus (SLE) fulfilling SLICC classification criteria, March 2020–March 2021, Saudi Arabia (88% female; mean age 36 [SD 13] years)
Participants
92 patients
Exposure
Telemedicine assessment vs in-person follow-up assessments
  • Telemedicinen = 92reference
  • Follow-up visitsn = 92
Outcome
Difference in SLEDAI-2K score
Methodological detailsnational prospective cohort, repeated measure model, adjusted for demographics, medications and changes in steroid doses, sensitivity analyses
  • National prospective cohort
  • Repeated measure model
  • Adjusted for demographics, medications and changes in steroid doses
  • Sensitivity analyses

Main finding

SLEDAI-2K score

Mean difference

−1.641

95% CI −2.773 to −0.510

P = 0.005*

Follow-up visitsvs Telemedicine
mean difference −1.641 (95% CI −2.773 to −0.510); P = 0.005*

As reported in the abstract

Observational data: associations, not effects.

Further findings

Results consistent in all sensitivity analyses

Original publication

Impact of telemedicine on disease activity assessment: A case-crossover study nested within a cohort of patients with systemic lupus erythematosus. Lupus. Published 3 November 2023. doi:10.1177/09612033231211855

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