Lupus & antiphospholipid syndrome
Red blood cell distribution width as a surrogate biomarker of damage and disease activity in patients with systemic lupus erythematosus
Main finding · RDW, after multivariable adjustmentResult — go to the resultBeta coefficient 0.8 % 95% CI 0.3–1Authors' conclusion
RDW may serve as a surrogate biomarker of accrual disease damage and activity in patients with SLE.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE) and age- and sex-matched healthy controls
- Participants
- 284 vs 181
- Exposure
- SLE vs age- and sex-matched healthy controls
- SLEn = 284
- Controlsn = 181reference
- Outcome
- RDW and its relationship with SLE disease characteristics, including composite scores of disease activity and damage
Methodological detailsage- and sex-matched healthy controls, multivariable analysis
- Age- and sex-matched healthy controls
- Multivariable analysis
Main finding
RDW, after multivariable adjustment
Beta coefficient
0.8 %
95% CI 0.3–1
P = 0.003
As reported in the abstract
Observational data: associations, not effects.
Further findings
Disease characteristics associated with RDW
- ENA, APS, prednisone and AZA use significantly associated with higher RDW after adjustment for confounders
Original publication
Red blood cell distribution width as a surrogate biomarker of damage and disease activity in patients with systemic lupus erythematosus. Clin Exp Rheumatol. Published 3 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →