Lupus & antiphospholipid syndrome
Impact of preeclampsia on infant and maternal health among women with rheumatic diseases
Authors' conclusion
We found preeclampsia was an important driver of adverse infant and maternal outcomes. While preeclampsia was particularly common among women with SLE in this cohort, the impact of preeclampsia on the infants of all women with rheumatic diseases was similarly severe.
Study context
- Population
- Women with systemic lupus erythematosus (SLE) and other rheumatic diseases with singleton deliveries (mean age 31 years, 35% non-Hispanic Black)
- Participants
- 263 singleton deliveries
- Exposure
- Women with preeclampsia vs without preeclampsia, SLE vs other rheumatic diseases
- Outcome
- Pregnancy and infant outcomes by preeclampsia status
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
- NICU admission twice as likely with preeclampsia
- twice
Observational data: associations, not effects.
Further findings
Preeclampsia prevalence
HCQ and aspirin use in SLE and preeclampsia
- No clear association of HCQ and aspirin with preeclampsia
Original publication
Impact of preeclampsia on infant and maternal health among women with rheumatic diseases. Lupus. Published 27 February 2024. doi:10.
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