Lupus & antiphospholipid syndrome
Association of race and ethnicity with mortality in adults with SLE: a systematic literature review and meta-analysis
Authors' conclusion
Overall, patients with SLE from Black or Indigenous racial and ethnic groups had higher mortality than those of White race and ethnicity. We observed no significant association in the mortality of Black patients compared with White patients from non-USA cohorts, but a scarcity of data outside of the USA was highlighted.
Study context
- Population
- Adults with SLE in studies reporting mortality stratified by racial and ethnic group
- Participants
- 85,578 adults37 studies
- Comparison
- Underserved racial and ethnic groups vs White race and ethnicity
- Outcome
- Mortality (pooled OR of death)
Methodological detailspairwise meta-analysis
- Pairwise meta-analysis
Pooled result
As reported in the abstract
Mortality
Each group vs whiteOdds ratio (95% CI)
Black
1.30(1.16–1.46)
Indigenous
1.47(1.11–1.94)
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Mortality, excluding USA studies (70% of studies were from the USA)Blackvs WhiteSignificant difference no longer seen | 0.84 (0.54–1.31) | |
| 0.512Odds ratio (log scale) |
Original publication
Association of race and ethnicity with mortality in adults with SLE: a systematic literature review and meta-analysis. Lupus Sci Med. Published 11 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →